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What is a lateral flow test?
Lateral flow tests, also known as lateral flow immunochromatographic assays or rapid tests, are simple devices intended to detect the presence of a target substance in a liquid sample without the need for specialized and costly equipment. These tests are widely used in medical diagnostics for home testing, point of care testing, or laboratory use.
What is a lateral flow reader?
Handheld diagnostic devices known as lateral flow readers are used by several companies to provide a fully quantitative assay result. By utilizing unique wavelengths of light for illumination in conjunction with either CMOS or CCD detection technology, a signal rich image can be produced of the actual test lines.
Can lateral flow assays report quantitative results?
One such handheld lateral flow device platform is made by Detekt Biomedical L.L.C.. Alternative non-optical techniques are also able to report quantitative assays results. One such example is a magnetic immunoassay (MIA) in the lateral flow test form also allows for getting a quantified result.
What is lateral flow immunochromatography?
Paul L.A.M. Corstjens, in Methods in Cell Biology, 2012 Lateral flow (LF) tests are frequently used for rapid delivery of qualitative diagnostic results. The detection sensitivity of these immunochromatography assays is largely dependent on the reporter technology.
What is a lateral flow assay?
Lateral flow assay (LFA) is a well-established platform for point-of-care (POC) testing due to its low cost and user friendliness. Conventional LFAs provide qualitative or semi-quantitative results and require dedicated instruments for quantitative detection.
What are the advantages of quantitation for the results of lateral flow?
Advantages of Quantitation for the Results of Lateral Flow Tests The potential for the wide use of quantitative immunochromatography is determined by the following features: Detecting test results and no subjectivity in their assessments (results are explicitly assessed even for faint staining).
What are the limitations of lateral flow tests?
However, traditional lateral flow tests rely on visual assessment and qualitative conclusion, which limit the objectivity and information output of the assays.
What are lateral flow rapid tests used for?
Due to their versatile nature, lateral flow rapid tests are used across a number of other industry sectors including pharma, environmental testing, animal health, food and feed testing, and plant and crop health. How does a lateral flow test work?